7U9B
Crystal structure of indoline 7 with KPC-2
Summary for 7U9B
Entry DOI | 10.2210/pdb7u9b/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, [(3S)-3-(1H-tetrazol-5-yl)-2,3-dihydro-1H-indol-1-yl][3-(trifluoromethyl)phenyl]methanone (3 entities in total) |
Functional Keywords | beta-lactamase, tetrazole, inhibitor, complex, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 28809.40 |
Authors | Akhtar, A.,Chen, Y. (deposition date: 2022-03-10, release date: 2023-03-15, Last modification date: 2023-10-25) |
Primary citation | DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R. Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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