7U91

Crystal structure of queuine salvage enzyme DUF2419, in complex with queuosine-5'-monophosphate

7U91 の概要

• エントリーDOI: 10.2210/pdb7u91/pdb
• 関連するPDBエントリー: 7U07
• 分子名称: Queuine salvage enzyme DUF2419, 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-7-(5-O-phosphono-beta-D-ribofuranosyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, AMMONIUM ION, ... (5 entities in total)
• 機能のキーワード: 7-deazaguanine salvage, queuosine, trna modification, hydrolase
• 由来する生物種: Sphaerobacter thermophilus DSM 20745
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75498.32

構造登録者

Hung, S.-H.,Swairjo, M.A. (登録日: 2022-03-09, 公開日: 2022-12-21, 最終更新日: 2023-10-25)

• 主引用文献: Hung, S.H.,Elliott, G.I.,Ramkumar, T.R.,Burtnyak, L.,McGrenaghan, C.J.,Alkuzweny, S.,Quaiyum, S.,Iwata-Reuyl, D.,Pan, X.,Green, B.D.,Kelly, V.P.,de Crecy-Lagard, V.,Swairjo, M.A.; Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.; Nucleic Acids Res., 51:935-951, 2023; PubMed: 36610787; DOI: 10.1093/nar/gkac1231

実験手法

X-RAY DIFFRACTION (2.4 Å)