7U61
Crystal Structure of Anti-Nicotine Antibody NIC311 Fab Complexed with Nicotine
Summary for 7U61
Entry DOI | 10.2210/pdb7u61/pdb |
Descriptor | NIC311 Fab Heavy Chain, NIC311 Fab Light Chain, (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, ... (5 entities in total) |
Functional Keywords | mab, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 47391.01 |
Authors | Rodarte, J.V.,Pancera, M.P.,Liban, T.L. (deposition date: 2022-03-03, release date: 2023-01-11, Last modification date: 2023-10-25) |
Primary citation | Rodarte, J.V.,Baehr, C.,Hicks, D.,Liban, T.L.,Weidle, C.,Rupert, P.B.,Jahan, R.,Wall, A.,McGuire, A.T.,Strong, R.K.,Runyon, S.,Pravetoni, M.,Pancera, M. Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding. Structure, 31:20-32.e5, 2023 Cited by PubMed: 36513069DOI: 10.1016/j.str.2022.11.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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