7U5P

CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A

Summary for 7U5P

• Entry DOI: 10.2210/pdb7u5p/pdb
• Descriptor: Activin receptor type-2A, Inhibin beta A chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: cell signaling, receptor-ligand complex, growth factor, receptor interaction, activin a, actriia, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 108955.52

Authors

Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E. (deposition date: 2022-03-02, release date: 2022-06-22, Last modification date: 2023-10-18)

• Primary citation: Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E.; Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition.; J.Biol.Chem., 298:102076-102076, 2022; PubMed: 35643319; DOI: 10.1016/j.jbc.2022.102076

Experimental method

X-RAY DIFFRACTION (3.14 Å)