7U5P

CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A

7U5P の概要

• エントリーDOI: 10.2210/pdb7u5p/pdb
• 分子名称: Activin receptor type-2A, Inhibin beta A chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: cell signaling, receptor-ligand complex, growth factor, receptor interaction, activin a, actriia, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 108955.52

構造登録者

Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E. (登録日: 2022-03-02, 公開日: 2022-06-22, 最終更新日: 2023-10-18)

• 主引用文献: Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E.; Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition.; J.Biol.Chem., 298:102076-102076, 2022; PubMed: 35643319; DOI: 10.1016/j.jbc.2022.102076

実験手法

X-RAY DIFFRACTION (3.14 Å)