7U0X

SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-13

7U0X の概要

• エントリーDOI: 10.2210/pdb7u0x/pdb
• EMDBエントリー: 26267
• 分子名称: Spike glycoprotein, mAb 002-13 heavy chain, mAb 002-13 Light chain, ... (5 entities in total)
• 機能のキーワード: sars-cov2 6p spike protein, immune complex, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 560854.57

構造登録者

Patel, A.,Ortlund, E. (登録日: 2022-02-19, 公開日: 2023-03-01, 最終更新日: 2023-09-13)

• 主引用文献: Patel, A.,Kumar, S.,Lai, L.,Chakravarthy, C.,Valanparambil, R.,Reddy, E.S.,Gottimukkala, K.,Bajpai, P.,Raju, D.R.,Edara, V.V.,Davis-Gardner, M.E.,Linderman, S.,Dixit, K.,Sharma, P.,Mantus, G.,Cheedarla, N.,Verkerke, H.P.,Frank, F.,Neish, A.S.,Roback, J.D.,Davis, C.W.,Wrammert, J.,Ahmed, R.,Suthar, M.S.,Sharma, A.,Murali-Krishna, K.,Chandele, A.,Ortlund, E.A.; Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.; Structure, 31:801-811.e5, 2023; PubMed: 37167972; DOI: 10.1016/j.str.2023.04.010

実験手法

ELECTRON MICROSCOPY (3.82 Å)