7U0A
Crystal Structure of C77G12 Fab in complex with SARS-CoV-2 S fusion peptide
Summary for 7U0A
Entry DOI | 10.2210/pdb7u0a/pdb |
Descriptor | SARS-CoV-2 S fusion peptide, Heavy chain Fab C77G12, Light chain Fab C77G12, ... (5 entities in total) |
Functional Keywords | sars-cov-2 spike, covid-19, fusion peptide, fab, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 48977.95 |
Authors | Tortorici, M.A.,Veesler, D. (deposition date: 2022-02-17, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Low, J.S.,Jerak, J.,Tortorici, M.A.,McCallum, M.,Pinto, D.,Cassotta, A.,Foglierini, M.,Mele, F.,Abdelnabi, R.,Weynand, B.,Noack, J.,Montiel-Ruiz, M.,Bianchi, S.,Benigni, F.,Sprugasci, N.,Joshi, A.,Bowen, J.E.,Stewart, C.,Rexhepaj, M.,Walls, A.C.,Jarrossay, D.,Morone, D.,Paparoditis, P.,Garzoni, C.,Ferrari, P.,Ceschi, A.,Neyts, J.,Purcell, L.A.,Snell, G.,Corti, D.,Lanzavecchia, A.,Veesler, D.,Sallusto, F. ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science, 377:735-742, 2022 Cited by PubMed: 35857703DOI: 10.1126/science.abq2679 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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