7TZU

Crystal structure of the E. coli thiM riboswitch bound to 1-(4-(piperazin-1-yl)pyridin-3-yl)-N-(quinoxalin-6-ylmethyl)methanamine (linked compound 38)

7TZU の概要

• エントリーDOI: 10.2210/pdb7tzu/pdb
• 分子名称: RNA (79-MER), 1-[4-(piperazin-1-yl)pyridin-3-yl]-N-[(quinoxalin-6-yl)methyl]methanamine, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: thim tpp riboswitch, rna
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27401.72

構造登録者

Nuthanakanti, A.,Serganov, A. (登録日: 2022-02-16, 公開日: 2022-05-25, 最終更新日: 2023-10-18)

• 主引用文献: Zeller, M.J.,Favorov, O.,Li, K.,Nuthanakanti, A.,Hussein, D.,Michaud, A.,Lafontaine, D.A.,Busan, S.,Serganov, A.,Aube, J.,Weeks, K.M.; SHAPE-enabled fragment-based ligand discovery for RNA.; Proc.Natl.Acad.Sci.USA, 119:e2122660119-e2122660119, 2022; PubMed: 35561226; DOI: 10.1073/pnas.2122660119

実験手法

X-RAY DIFFRACTION (2.87 Å)