7TZP

Crystal Structure of Putataive Short-Chain Dehydrogenase/Reductase (FabG) from Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 in Complex with NADH

Summary for 7TZP

• Entry DOI: 10.2210/pdb7tzp/pdb
• Descriptor: 3-oxoacyl-ACP reductase, POTASSIUM ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, fabg, nadh, biosynthetic protein
• Biological source: Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
• Total number of polymer chains: 8
• Total formula weight: 215608.88

Authors

Minasov, G.,Shuvalova, L.,Dubrovska, I.,Kiryukhina, O.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2022-02-16, release date: 2022-03-02, Last modification date: 2024-10-23)

Primary citation

Inniss, N.L.,Kochan, T.J.,Minasov, G.,Wawrzak, Z.,Chang, C.,Tan, K.,Shuvalova, L.,Kiryukhina, O.,Pshenychnyi, S.,Wu, R.,Dubrovska, I.,Babnigg, G.,Endres, M.,Anderson, W.F.,Hauser, A.R.,Joachimiak, A.,Satchell, K.J.F.
A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
Microbiol Resour Announc, 12:e0101322-e0101322, 2023

PubMed Abstract: Klebsiella pneumoniae is a leading cause of antibiotic-resistant-associated deaths in the world. Here, we report the deposition of 14 structures of enzymes from both the core and accessory genomes of sequence type 23 (ST23) K1 hypervirulent K. pneumoniae.

PubMed: 36695589
DOI: 10.1128/mra.01013-22

Experimental method

X-RAY DIFFRACTION (2.6 Å)