7TXS

X-ray structure of the VioB N-aetyltransferase from Acinetobacter baumannii in the presence of a reaction intermediate

Summary for 7TXS

• Entry DOI: 10.2210/pdb7txs/pdb
• Related: 7txp 7txq
• Descriptor: VioB, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methyl (3R)-4-({3-[(2-{[(1S)-1-{[(2R,3S,4S,5R,6R)-4,5-dihydroxy-6-{[(R)-hydroxy{[(R)-hydroxy{[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)oxolan-2-yl]methoxy}phosphoryl]oxy}phosphoryl]oxy}-2-methyloxan-3-yl]amino}ethyl]sulfanyl}ethyl)amino]-3-oxopropyl}amino)-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate (non-preferred name), SODIUM ION, ... (4 entities in total)
• Functional Keywords: 4-amino-4, 6-dideoxy-d-glucose, beta helix, acinetobacter baumannii, n-acetyltransferase, transferase
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 1
• Total formula weight: 24738.76

Authors

Herkert, N.R.,Thoden, J.B.,Holden, H.M. (deposition date: 2022-02-09, release date: 2022-03-09, Last modification date: 2023-10-18)

• Primary citation: Herkert, N.R.,Thoden, J.B.,Holden, H.M.; Structure and function of an N-acetyltransferase from the human pathogen Acinetobacter baumannii isolate BAL_212.; Proteins, 90:1594-1605, 2022; PubMed: 35277885; DOI: 10.1002/prot.26334

Experimental method

X-RAY DIFFRACTION (1.25 Å)