7TU7

Structure of the L. blandensis dGTPase H125A mutant bound to dGTP

Summary for 7TU7

Entry DOI	10.2210/pdb7tu7/pdb
EMDB information	26126 26127 26128 26129
Descriptor	dGTP triphosphohydrolase, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywords	dgtpase, nucleotide binding, hydrolase
Biological source	Leeuwenhoekiella blandensis MED217
Total number of polymer chains	6
Total formula weight	319417.63
Authors	Klemm, B.P.,Sikkema, A.P.,Hsu, A.L.,Borgnia, M.J.,Schaaper, R.M. (deposition date: 2022-02-02, release date: 2022-06-01, Last modification date: 2024-02-21)
Primary citation	Klemm, B.P.,Sikkema, A.P.,Hsu, A.L.,Horng, J.C.,Hall, T.M.T.,Borgnia, M.J.,Schaaper, R.M. High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298:102073-102073, 2022 Cited by PubMed: 35643313 DOI: 10.1016/j.jbc.2022.102073 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation