7TTW
50S ribosomal subunit from Staphylococcus aureus containing double mutation in uL3 imparting linezolid resistance
Summary for 7TTW
Entry DOI | 10.2210/pdb7ttw/pdb |
Related | 7TTU |
EMDB information | 26125 |
Descriptor | 50S ribosomal protein L19, 50S ribosomal protein L28, 50S ribosomal protein L29, ... (27 entities in total) |
Functional Keywords | 50s subunit, antibiotic resistance, linezolid, ribosome |
Biological source | Staphylococcus aureus More |
Total number of polymer chains | 27 |
Total formula weight | 1307599.65 |
Authors | Belousoff, M.J.,Piper, S.,Johnson, R. (deposition date: 2022-02-02, release date: 2022-07-06, Last modification date: 2022-09-14) |
Primary citation | Perlaza-Jimenez, L.,Tan, K.S.,Piper, S.J.,Johnson, R.M.,Bamert, R.S.,Stubenrauch, C.J.,Wright, A.,Lupton, D.,Lithgow, T.,Belousoff, M.J. A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid. Microbiol Spectr, 10:e0058322-e0058322, 2022 Cited by PubMed: 35736238DOI: 10.1128/spectrum.00583-22 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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