7TNU

The crystal structure of F298V CYP199A4 bound to 4-cyclohexylbenzoic acid

7TNU の概要

• エントリーDOI: 10.2210/pdb7tnu/pdb
• 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 4-cyclohexylbenzoic acid, ... (5 entities in total)
• 機能のキーワード: cytochrome p450, f298v mutant, cyp199a4, 4-cyclohexylbenzoic acid, oxidoreductase
• 由来する生物種: Rhodopseudomonas palustris HaA2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45395.59

構造登録者

Podgorski, M.,Bell, S.G. (登録日: 2022-01-21, 公開日: 2023-01-04, 最終更新日: 2023-10-25)

• 主引用文献: Coleman, T.,Lee, J.Z.H.,Kirk, A.M.,Doherty, D.Z.,Podgorski, M.N.,Pinidiya, D.K.,Bruning, J.B.,De Voss, J.J.,Krenske, E.H.,Bell, S.G.; Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.; Chemistry, 28:e202201895-e202201895, 2022; PubMed: 36043399; DOI: 10.1002/chem.202201895

実験手法

X-RAY DIFFRACTION (1.584 Å)