7TJH
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain
Summary for 7TJH
Entry DOI | 10.2210/pdb7tjh/pdb |
EMDB information | 25924 25925 25926 25927 25928 |
Descriptor | Origin recognition complex subunit 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (12 entities in total) |
Functional Keywords | initiator, helicase loader, aaa+ atpase, replication-dna complex, replication/dna |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Total number of polymer chains | 9 |
Total formula weight | 527392.38 |
Authors | Schmidt, J.M.,Yang, R.,Kumar, A.,Hunker, O.,Bleichert, F. (deposition date: 2022-01-16, release date: 2022-10-05, Last modification date: 2024-06-05) |
Primary citation | Schmidt, J.M.,Yang, R.,Kumar, A.,Hunker, O.,Seebacher, J.,Bleichert, F. A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13:1059-1059, 2022 Cited by PubMed: 35217664DOI: 10.1038/s41467-022-28695-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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