7TJH

S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain

7TJH の概要

• エントリーDOI: 10.2210/pdb7tjh/pdb
• EMDBエントリー: 25924 25925 25926 25927 25928
• 分子名称: Origin recognition complex subunit 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (12 entities in total)
• 機能のキーワード: initiator, helicase loader, aaa+ atpase, replication-dna complex, replication/dna
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 527392.38

構造登録者

Schmidt, J.M.,Yang, R.,Kumar, A.,Hunker, O.,Bleichert, F. (登録日: 2022-01-16, 公開日: 2022-10-05)

• 主引用文献: Schmidt, J.M.,Yang, R.,Kumar, A.,Hunker, O.,Seebacher, J.,Bleichert, F.; A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.; Nat Commun, 13:1059-1059, 2022; PubMed: 35217664; DOI: 10.1038/s41467-022-28695-w

実験手法

ELECTRON MICROSCOPY (2.5 Å)