7TJ9

Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN

7TJ9 の概要

• エントリーDOI: 10.2210/pdb7tj9/pdb
• EMDBエントリー: 25919 25920
• 分子名称: Sodium channel protein type 7 subunit alpha, Sodium channel subunit beta-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: sodium channel, nav, ion channel, transport protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 234368.40

構造登録者

Noland, C.L.,Kschonsak, M.,Ciferri, C.,Payandeh, J. (登録日: 2022-01-14, 公開日: 2022-03-30)

• 主引用文献: Noland, C.L.,Chua, H.C.,Kschonsak, M.,Heusser, S.A.,Braun, N.,Chang, T.,Tam, C.,Tang, J.,Arthur, C.P.,Ciferri, C.,Pless, S.A.,Payandeh, J.; Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.; Nat Commun, 13:1416-1416, 2022; PubMed: 35301303; DOI: 10.1038/s41467-022-28984-4

実験手法

ELECTRON MICROSCOPY (2.9 Å)