7TJ3

Crystal structure of a dihydrofolate reductase folA from Stenotrophomonas maltophilia bound to NADP and p218

Summary for 7TJ3

• Entry DOI: 10.2210/pdb7tj3/pdb
• Descriptor: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ... (6 entities in total)
• Functional Keywords: niaid, structural genomics, dhfr, inhibitor, oxidoreductase, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Stenotrophomonas maltophilia K279a
• Total number of polymer chains: 1
• Total formula weight: 20524.88

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2022-01-14, release date: 2022-11-23, Last modification date: 2023-10-25)

• Primary citation: Edwards, T.E.,deBouver, N.D.,Horanyi, P.S.,Lorimer, D.D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID); Crystal structure of a dihydrofolate reductase folA from Stenotrophomonas maltophilia bound to NADP and p218; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)