7TEW

Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)

7TEW の概要

• エントリーDOI: 10.2210/pdb7tew/pdb
• EMDBエントリー: 25853
• 分子名称: Spike glycoprotein, Processed angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: sars-cov-2, glycoprotein, fusion protein, viral protein, ace2
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 214115.73

構造登録者

Zhu, X.,Saville, J.W.,Mannar, D.,Srivastava, S.S.,Berezuk, A.M.,Demers, J.P.,Zhou, S.,Tuttle, K.S.,Subramaniam, S. (登録日: 2022-01-06, 公開日: 2022-03-16)

• 主引用文献: Saville, J.W.,Mannar, D.,Zhu, X.,Srivastava, S.S.,Berezuk, A.M.,Demers, J.P.,Zhou, S.,Tuttle, K.S.,Sekirov, I.,Kim, A.,Li, W.,Dimitrov, D.S.,Subramaniam, S.; Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants.; Nat Commun, 13:742-742, 2022; PubMed: 35136050; DOI: 10.1038/s41467-022-28324-6

実験手法

ELECTRON MICROSCOPY (3.52 Å)