7TDB
Crystal structure of the E. coli thiM riboswitch in complex with thiamine bisphosphonate, manganese ions
Summary for 7TDB
Entry DOI | 10.2210/pdb7tdb/pdb |
Descriptor | thiM riboswitch RNA (83-MER), [2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethoxy-oxidanyl-phosphoryl]methylphosphonic acid, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | rna |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 27594.89 |
Authors | Nuthanakanti, A.,Serganov, A. (deposition date: 2021-12-30, release date: 2022-02-16, Last modification date: 2023-10-18) |
Primary citation | Zeller, M.J.,Nuthanakanti, A.,Li, K.,Aube, J.,Serganov, A.,Weeks, K.M. Subsite Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery. Acs Chem.Biol., 17:438-448, 2022 Cited by PubMed: 35060698DOI: 10.1021/acschembio.1c00880 PDB entries with the same primary citation |
Experimental method |
Structure validation
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