7TCQ
Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide
Summary for 7TCQ
Entry DOI | 10.2210/pdb7tcq/pdb |
Descriptor | Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, Pegylated spike S2 peptide, ... (7 entities in total) |
Functional Keywords | sars-cov-2, spike, antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 6 |
Total formula weight | 97942.59 |
Authors | Zhou, T.,Kwong, P.D. (deposition date: 2021-12-28, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Shi, W.,Wang, L.,Zhou, T.,Sastry, M.,Yang, E.S.,Zhang, Y.,Chen, M.,Chen, X.,Choe, M.,Creanga, A.,Leung, K.,Olia, A.S.,Pegu, A.,Rawi, R.,Schon, A.,Shen, C.H.,Stancofski, E.D.,Talana, C.A.,Teng, I.T.,Wang, S.,Corbett, K.S.,Tsybovsky, Y.,Mascola, J.R.,Kwong, P.D. Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability. Structure, 30:1233-, 2022 Cited by PubMed: 35841885DOI: 10.1016/j.str.2022.06.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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