7TBU
Crystal structure of the 5-enolpyruvate-shikimate-3-phosphate synthase (EPSPS) domain of Aro1 from Candida albicans in complex with shikimate-3-phosphate
Summary for 7TBU
Entry DOI | 10.2210/pdb7tbu/pdb |
Descriptor | 5-enolpyruvylshikimate-3-phosphate synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SHIKIMATE-3-PHOSPHATE, ... (4 entities in total) |
Functional Keywords | chorismate biosynthesis, structural genomics, center for structural genomics of infectious diseases, csgid, transferase |
Biological source | Candida albicans Ca6 |
Total number of polymer chains | 2 |
Total formula weight | 98287.31 |
Authors | Stogios, P.J.,Evdokimova, E.,Michalska, K.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-12-22, release date: 2022-03-16, Last modification date: 2023-10-25) |
Primary citation | Stogios, P.J.,Liston, S.D.,Semper, C.,Quade, B.,Michalska, K.,Evdokimova, E.,Ram, S.,Otwinowski, Z.,Borek, D.,Cowen, L.E.,Savchenko, A. Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5:-, 2022 Cited by PubMed: 35512834DOI: 10.26508/lsa.202101358 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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