7TBU

Crystal structure of the 5-enolpyruvate-shikimate-3-phosphate synthase (EPSPS) domain of Aro1 from Candida albicans in complex with shikimate-3-phosphate

7TBU の概要

• エントリーDOI: 10.2210/pdb7tbu/pdb
• 分子名称: 5-enolpyruvylshikimate-3-phosphate synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SHIKIMATE-3-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: chorismate biosynthesis, structural genomics, center for structural genomics of infectious diseases, csgid, transferase
• 由来する生物種: Candida albicans Ca6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98287.31

構造登録者

Stogios, P.J.,Evdokimova, E.,Michalska, K.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2021-12-22, 公開日: 2022-03-16, 最終更新日: 2023-10-25)

• 主引用文献: Stogios, P.J.,Liston, S.D.,Semper, C.,Quade, B.,Michalska, K.,Evdokimova, E.,Ram, S.,Otwinowski, Z.,Borek, D.,Cowen, L.E.,Savchenko, A.; Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans.; Life Sci Alliance, 5:-, 2022; PubMed: 35512834; DOI: 10.26508/lsa.202101358

実験手法

X-RAY DIFFRACTION (1.85 Å)