7TAH

Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526091 (no/low occupancy-no inhibitor modeled)

7TAH の概要

• エントリーDOI: 10.2210/pdb7tah/pdb
• EMDBエントリー: 25774
• 分子名称: viral protein 1, viral protein 3, viral protein 2, ... (4 entities in total)
• 機能のキーワード: virus, ev-d68, acute flaccid myelitis, afm, inhibitor, antiviral, structural genomics, center for structural genomics of infectious diseases, csgid
• 由来する生物種: enterovirus D68; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 93842.08

構造登録者

Fu, J.,Klose, T.,Kuhn, R.J.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2021-12-20, 公開日: 2023-01-25, 最終更新日: 2024-06-05)

• 主引用文献: Lane, T.,Fu, J.,Sherry, B.,Tarbet, B.,Hurst, B.L.,Riabova, O.,Kazakova, E.,Egorova, A.,Clarke, P.,Leser, S.,Frost, J.,Rudy, M.,Tyler, K.,Klose, T.,Kuhn, R.J.,Makarov, V.,Ekins, S.; Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68; To Be Published,

実験手法

ELECTRON MICROSCOPY (2.3 Å)