7TAF
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092
Summary for 7TAF
Entry DOI | 10.2210/pdb7taf/pdb |
EMDB information | 25772 |
Descriptor | viral protein 1, viral protein 3, viral protein 2, ... (5 entities in total) |
Functional Keywords | virus, ev-d68, acute flaccid myelitis, afm, inhibitor, antiviral, structural genomics, center for structural genomics of infectious diseases, csgid, virus-inhibitor complex, virus/inhibitor |
Biological source | enterovirus D68 More |
Total number of polymer chains | 4 |
Total formula weight | 94266.45 |
Authors | Fu, J.,Klose, T.,Kuhn, R.J.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-12-20, release date: 2023-01-25, Last modification date: 2024-06-05) |
Primary citation | Lane, T.,Fu, J.,Sherry, B.,Tarbet, B.,Hurst, B.L.,Riabova, O.,Kazakova, E.,Egorova, A.,Clarke, P.,Leser, S.,Frost, J.,Rudy, M.,Tyler, K.,Klose, T.,Kuhn, R.J.,Makarov, V.,Ekins, S. Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68 To Be Published, |
Experimental method | ELECTRON MICROSCOPY (2 Å) |
Structure validation
Download full validation report