7TA0

Human Ornithine Aminotransferase (hOAT) soaked with 5-aminovaleric acid

Summary for 7TA0

Entry DOI	10.2210/pdb7ta0/pdb
Descriptor	Ornithine aminotransferase, mitochondrial, 5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	human ornithine aminotransferase, hoat, oat, plp, 5-aminovaleric acid, soaking, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	147015.81
Authors	Butrin, A.,Liu, D. (deposition date: 2021-12-20, release date: 2022-05-04, Last modification date: 2023-10-18)
Primary citation	Butrin, A.,Butrin, A.,Wawrzak, Z.,Moran, G.R.,Liu, D. Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298:101969-101969, 2022 Cited by PubMed: 35460691 DOI: 10.1016/j.jbc.2022.101969 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation