7T8Z

Structure of Class A sortase from Streptococcus pyogenes bound to lipid II mimetic, LPATA: Thr-out conformation

7T8Z の概要

• エントリーDOI: 10.2210/pdb7t8z/pdb
• 関連するBIRD辞書のPRD_ID: PRD_002489
• 分子名称: Sortase, BE2-LEU-PRO-ALA-THR-ALA-ALA, ACE-ALA-ZGL-LYS-DAL-DAL, ... (4 entities in total)
• 機能のキーワード: sortase-fold, hydrolase, sortase, eight-stranded beta barrel, transpeptidase, housekeeping sortase, surface protein
• 由来する生物種: Streptococcus pyogenes; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 19797.46

構造登録者

Piper, I.M.,Antos, J.M.,Amacher, J.F. (登録日: 2021-12-17, 公開日: 2022-09-07, 最終更新日: 2023-11-15)

• 主引用文献: Johnson, D.A.,Piper, I.M.,Vogel, B.A.,Jackson, S.N.,Svendsen, J.E.,Kodama, H.M.,Lee, D.E.,Lindblom, K.M.,McCarty, J.,Antos, J.M.,Amacher, J.F.; Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.; J.Biol.Chem., 298:102446-102446, 2022; PubMed: 36055407; DOI: 10.1016/j.jbc.2022.102446

実験手法

X-RAY DIFFRACTION (1.9 Å)