7T8Y

Structure of Class A sortase from Streptococcus pyogenes bound to lipid II mimetic, LPATA: Thr-in conformation

Summary for 7T8Y

Entry DOI	10.2210/pdb7t8y/pdb
Related PRD ID	PRD_002489
Descriptor	Sortase, BE2-LEU-PRO-ALA-THR-ALA-ALA, ACE-ALA-ZGL-LYS-DAL-DAL, ... (4 entities in total)
Functional Keywords	sortase-fold, hydrolase, sortase, eight-stranded beta barrel, transpeptidase, housekeeping sortase, surface protein
Biological source	Streptococcus pyogenes More
Total number of polymer chains	3
Total formula weight	19797.46
Authors	Piper, I.M.,Antos, J.M.,Amacher, J.F. (deposition date: 2021-12-17, release date: 2022-09-07, Last modification date: 2023-11-15)
Primary citation	Johnson, D.A.,Piper, I.M.,Vogel, B.A.,Jackson, S.N.,Svendsen, J.E.,Kodama, H.M.,Lee, D.E.,Lindblom, K.M.,McCarty, J.,Antos, J.M.,Amacher, J.F. Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition. J.Biol.Chem., 298:102446-102446, 2022 Cited by PubMed: 36055407 DOI: 10.1016/j.jbc.2022.102446 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation