7T4N

Structure of dimeric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant

Summary for 7T4N

Entry DOI	10.2210/pdb7t4n/pdb
EMDB information	25681
Descriptor	Serine/threonine-protein kinase PINK1, putative (1 entity in total)
Functional Keywords	pink1, kinase, transferase, mitophagy, parkinson's disease, ubiquitin, phosphorylation, phospho-ubiquitin
Biological source	Pediculus humanus corporis (human body louse)
Total number of polymer chains	2
Total formula weight	105859.23
Authors	Gan, Z.Y.,Leis, A.,Dewson, G.,Glukhova, A.,Komander, D. (deposition date: 2021-12-10, release date: 2022-01-12, Last modification date: 2024-02-28)
Primary citation	Gan, Z.Y.,Callegari, S.,Cobbold, S.A.,Cotton, T.R.,Mlodzianoski, M.J.,Schubert, A.F.,Geoghegan, N.D.,Rogers, K.L.,Leis, A.,Dewson, G.,Glukhova, A.,Komander, D. Activation mechanism of PINK1. Nature, 602:328-335, 2022 Cited by PubMed: 34933320 DOI: 10.1038/s41586-021-04340-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.35 Å)

Structure validation