7T2A

Crystal structure of HLA-DP4 in complex with Ply

Summary for 7T2A

• Entry DOI: 10.2210/pdb7t2a/pdb
• Descriptor: HLA class II histocompatibility antigen, DP alpha 1 chain, HLA class II histocompatibility antigen, DP beta 1 chain, Pneumolysin-derived peptide, ... (4 entities in total)
• Functional Keywords: phla complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 90256.63

Authors

Ciacchi, L.,Farenc, C.,Petersen, J.,Reid, H.H.,Rossjohn, J. (deposition date: 2021-12-03, release date: 2022-12-28, Last modification date: 2023-10-25)

• Primary citation: Ciacchi, L.,van de Garde, M.D.B.,Ladell, K.,Farenc, C.,Poelen, M.C.M.,Miners, K.L.,Llerena, C.,Reid, H.H.,Petersen, J.,Price, D.A.,Rossjohn, J.,van Els, C.A.C.M.; CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.; Immunity, 56:1082-1097.e6, 2023; PubMed: 37100059; DOI: 10.1016/j.immuni.2023.03.020

Experimental method

X-RAY DIFFRACTION (3.04 Å)