7T1E

Structure of monomeric and dimeric human CCL20

Summary for 7T1E

• Entry DOI: 10.2210/pdb7t1e/pdb
• Descriptor: C-C motif chemokine 20, GLYCEROL, SUCCINIC ACID, ... (5 entities in total)
• Functional Keywords: chemokine, ccr6, th17, inflammation, autoimmune, psoriasis, psoriatic arthritis, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 5
• Total formula weight: 41535.12

Authors

Peterson, F.C.,Riutta, S.J.,Volkman, B.F. (deposition date: 2021-12-01, release date: 2022-12-14, Last modification date: 2024-06-26)

• Primary citation: Shi, Z.R.,Mabuchi, T.,Riutta, S.J.,Wu, X.,Peterson, F.C.,Volkman, B.F.,Hwang, S.T.; The Chemokine, CCL20, and Its Receptor, CCR6, in the Pathogenesis and Treatment of Psoriasis and Psoriatic Arthritis; J Psoriasis Psoriatic Arthritis, 8:107-117, 2023; DOI: 10.1177/24755303231159106

Experimental method

X-RAY DIFFRACTION (1.459 Å)