7SVG
Bile Salt Hydrolase A from Lactobacillus gasseri with chenodeoxycholate and taurine bound
Summary for 7SVG
Entry DOI | 10.2210/pdb7svg/pdb |
Descriptor | Choloylglycine hydrolase, 2-AMINOETHANESULFONIC ACID, CHENODEOXYCHOLIC ACID, ... (4 entities in total) |
Functional Keywords | bile salt hydrolase, hydrolase |
Biological source | Lactobacillus gasseri |
Total number of polymer chains | 4 |
Total formula weight | 145311.35 |
Authors | Walker, M.E.,Redinbo, M.R. (deposition date: 2021-11-19, release date: 2023-01-25, Last modification date: 2023-11-15) |
Primary citation | Foley, M.H.,Walker, M.E.,Stewart, A.K.,O'Flaherty, S.,Gentry, E.C.,Patel, S.,Beaty, V.V.,Allen, G.,Pan, M.,Simpson, J.B.,Perkins, C.,Vanhoy, M.E.,Dougherty, M.K.,McGill, S.K.,Gulati, A.S.,Dorrestein, P.C.,Baker, E.S.,Redinbo, M.R.,Barrangou, R.,Theriot, C.M. Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut. Nat Microbiol, 8:611-628, 2023 Cited by PubMed: 36914755DOI: 10.1038/s41564-023-01337-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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