7SQW

Structure of the KcsA-W67F mutant with the activation gate in the closed conformation

7SQW の概要

• エントリーDOI: 10.2210/pdb7sqw/pdb
• 分子名称: Antibody Fragment, KcsA potassium channel, NONAN-1-OL, ... (6 entities in total)
• 機能のキーワード: channel, fab complex, c-type inactivation, membrane protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 58569.10

構造登録者

Cuello, L.G.,Labro, A.J. (登録日: 2021-11-07, 公開日: 2022-10-12, 最終更新日: 2023-10-18)

• 主引用文献: Coonen, L.,Martinez-Morales, E.,Van De Sande, D.V.,Snyders, D.J.,Cortes, D.M.,Cuello, L.G.,Labro, A.J.; The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.; Sci Adv, 8:eabn1731-eabn1731, 2022; PubMed: 36112676; DOI: 10.1126/sciadv.abn1731

実験手法

X-RAY DIFFRACTION (3.21 Å)