7SNT
2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine
Summary for 7SNT
Entry DOI | 10.2210/pdb7snt/pdb |
Descriptor | Oplophorus-luciferin 2-monooxygenase catalytic subunit, (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine (3 entities in total) |
Functional Keywords | oplophorus bioluminescent protein, nanoluc luciferase, nluc, coelenterazine, furimazine, beta-barrel, oxidoreductase, 3-methoxy-furimazine |
Biological source | Oplophorus gracilirostris (Luminous shrimp) |
Total number of polymer chains | 2 |
Total formula weight | 39253.78 |
Authors | Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Wood, M.G.,Unch, J.,Encell, L.P.,Wood, K.V. (deposition date: 2021-10-28, release date: 2022-11-16, Last modification date: 2023-10-18) |
Primary citation | Encell, L.P.,Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Wood, M.G.,Wood, K.V. 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine To be published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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