7SNT

2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine

Summary for 7SNT

• Entry DOI: 10.2210/pdb7snt/pdb
• Descriptor: Oplophorus-luciferin 2-monooxygenase catalytic subunit, (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine (3 entities in total)
• Functional Keywords: oplophorus bioluminescent protein, nanoluc luciferase, nluc, coelenterazine, furimazine, beta-barrel, oxidoreductase, 3-methoxy-furimazine
• Biological source: Oplophorus gracilirostris (Luminous shrimp)
• Total number of polymer chains: 2
• Total formula weight: 39253.78

Authors

Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Wood, M.G.,Unch, J.,Encell, L.P.,Wood, K.V. (deposition date: 2021-10-28, release date: 2022-11-16, Last modification date: 2023-10-18)

• Primary citation: Encell, L.P.,Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Wood, M.G.,Wood, K.V.; 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine; To be published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)