7SMZ

X-ray crystal structure of CYP142A3 from Mycobacterium Marinum in complex with 4-cholesten-3-one

7SMZ の概要

• エントリーDOI: 10.2210/pdb7smz/pdb
• 分子名称: Cytochrome P450 142A3, (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
• 機能のキーワード: substrate bound, oxidoreductase
• 由来する生物種: Mycobacterium marinum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93469.37

構造登録者

Ghith, A.,Bruning, J.B.,Bell, S.G. (登録日: 2021-10-27, 公開日: 2022-09-14, 最終更新日: 2023-10-18)

• 主引用文献: Ghith, A.,Doherty, D.Z.,Bruning, J.B.,Russell, R.A.,De Voss, J.J.,Bell, S.G.; The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum.; Acs Infect Dis., 8:1606-1617, 2022; PubMed: 35881654; DOI: 10.1021/acsinfecdis.2c00215

実験手法

X-RAY DIFFRACTION (2.04 Å)