7SMU

Crystal Structure of Consomatin-Ro1

7SMU の概要

• エントリーDOI: 10.2210/pdb7smu/pdb
• 分子名称: Consomatin-Ro1, 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaoctatetracontane-1,48-diol (3 entities in total)
• 機能のキーワード: cone snail, venom, consomatin-ro1, somatostatin, sst mimetic, disulfide, toxin
• 由来する生物種: Conus rolani
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 10203.94

構造登録者

Ramiro, I.B.L.,Whitby, F.G.,Hill, C.P.,Safavi-Hemami, H.,Concepcion, G.P.,Olivera, B.M. (登録日: 2021-10-26, 公開日: 2022-04-13)

• 主引用文献: Ramiro, I.B.L.,Bjorn-Yoshimoto, W.E.,Imperial, J.S.,Gajewiak, J.,Salcedo, P.F.,Watkins, M.,Taylor, D.,Resager, W.,Ueberheide, B.,Brauner-Osborne, H.,Whitby, F.G.,Hill, C.P.,Martin, L.F.,Patwardhan, A.,Concepcion, G.P.,Olivera, B.M.,Safavi-Hemami, H.; Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads.; Sci Adv, 8:eabk1410-eabk1410, 2022; PubMed: 35319982; DOI: 10.1126/sciadv.abk1410

実験手法

X-RAY DIFFRACTION (1.95 Å)