7SJS

Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8

7SJS の概要

• エントリーDOI: 10.2210/pdb7sjs/pdb
• 分子名称: CC40.8 Fab heavy chain, CC40.8 Fab light chain, stem helix peptide of Spike protein S2', ... (7 entities in total)
• 機能のキーワード: sars-cov-2, antibody, spike, s2, stem helix, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49177.54

構造登録者

Yuan, M.,Wilson, I.A. (登録日: 2021-10-18, 公開日: 2022-01-12, 最終更新日: 2023-10-18)

• 主引用文献: Zhou, P.,Yuan, M.,Song, G.,Beutler, N.,Shaabani, N.,Huang, D.,He, W.T.,Zhu, X.,Callaghan, S.,Yong, P.,Anzanello, F.,Peng, L.,Ricketts, J.,Parren, M.,Garcia, E.,Rawlings, S.A.,Smith, D.M.,Nemazee, D.,Teijaro, J.R.,Rogers, T.F.,Wilson, I.A.,Burton, D.R.,Andrabi, R.; A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.; Sci Transl Med, 14:eabi9215-eabi9215, 2022; PubMed: 35133175; DOI: 10.1126/scitranslmed.abi9215

実験手法

X-RAY DIFFRACTION (1.612 Å)