7SG0
W316 TCR in complex with HLA-DQ2-omega1
Summary for 7SG0
| Entry DOI | 10.2210/pdb7sg0/pdb |
| Descriptor | HLA class II histocompatibility antigen, DQ alpha 1 chain, MHC class II HLA-DQ-beta-1, DQ2-glia-omega1 peptide, ... (7 entities in total) |
| Functional Keywords | tcr-phla complex, celiac disease, immune system |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 96141.91 |
| Authors | Ciacchi, L.,Farenc, C.,Petersen, J.,Reid, H.H.,Rossjohn, J. (deposition date: 2021-10-04, release date: 2022-02-23, Last modification date: 2023-12-20) |
| Primary citation | Ciacchi, L.,Farenc, C.,Dahal-Koirala, S.,Petersen, J.,Sollid, L.M.,Reid, H.H.,Rossjohn, J. Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease. J.Biol.Chem., 298:101619-101619, 2022 Cited by PubMed: 35065967DOI: 10.1016/j.jbc.2022.101619 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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