7SFO

Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and GRIP Peptide

Summary for 7SFO

• Entry DOI: 10.2210/pdb7sfo/pdb
• Descriptor: Estrogen receptor, Nuclear receptor coactivator 2, 3-{[(2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methyl}phenol, ... (4 entities in total)
• Functional Keywords: estrogen receptor, hormone, breast cancer, alpha helical bundle, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 60169.69

Authors

Joyner, C.,Reddy, V.K.,Wilson, T.,Fanning, S.W. (deposition date: 2021-10-04, release date: 2022-10-12, Last modification date: 2023-10-18)

• Primary citation: Fanning, S.W.; Estrogen Receptor Alpha; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)