7SFI
SARS-CoV-2 Main Protease (Mpro) in Complex with ML104
7SFI の概要
エントリーDOI | 10.2210/pdb7sfi/pdb |
分子名称 | 3C-like proteinase, (1R,2S,5S)-N-{(2S,3R)-4-amino-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-6,6-dimethyl-3-[N-(2,4,6-trifluorophenyl)glycyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, CHLORIDE ION, ... (5 entities in total) |
機能のキーワード | sarscov2, sars-cov-2, coronavirus, main protease, protease, mpro, 3c-like proteinase, cl3pro, inhibitor, complex, covalent, adduct, ml104, ketoamide, peptidomimetic, viral protein |
由来する生物種 | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 34426.60 |
構造登録者 | |
主引用文献 | Westberg, M.,Su, Y.,Zou, X.,Rustagi, A.,Beck, A.,Ning, L.,Fernandez, D.,Blish, C.,Lin, M.Z. Rational design of a new class of protease inhibitors for the potential treatment of coronavirus diseases To Be Published, |
実験手法 | X-RAY DIFFRACTION (1.95 Å) |
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