7SCE
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP
7SCE の概要
エントリーDOI | 10.2210/pdb7sce/pdb |
分子名称 | Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... (4 entities in total) |
機能のキーワード | sulfotransferase, heparan sulfate, oligosaccharide, complex, transferase, transferase-substrate complex, transferase/substrate |
由来する生物種 | Escherichia coli 詳細 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 44838.95 |
構造登録者 | Wander, R.,Kaminski, A.M.,Krahn, J.M.,Liu, J.,Pedersen, L.C. (登録日: 2021-09-27, 公開日: 2022-01-19, 最終更新日: 2023-10-18) |
主引用文献 | Wander, R.,Kaminski, A.M.,Wang, Z.,Stancanelli, E.,Xu, Y.,Pagadala, V.,Li, J.,Krahn, J.M.,Pham, T.Q.,Liu, J.,Pedersen, L.C. Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate Acs Catalysis, 11:14956-14966, 2021 Cited by DOI: 10.1021/acscatal.1c04520主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.75 Å) |
構造検証レポート
検証レポート(詳細版)
をダウンロード
![ダウンロード](/newweb/media/icons/dl.png)