7S8J

PHOSPHOPEPTIDE-SPECIFIC LC13 TCR, ORTHORHOMBIC CRYSTAL FORM

7S8J の概要

• エントリーDOI: 10.2210/pdb7s8j/pdb
• 分子名称: TRAV27_LC13 TCR ALPHA CHAIN, TRBV27_LC13 TCR BETA CHAIN, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: hla, mll peptide, hla-b*07:02, hla-b7, immunity, immune system, phosphopeptide, cancer, neoantigen, tcr
• 由来する生物種: Homo sapiens (HUMAN); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50437.98

構造登録者

Patskovska, L.,Patskovsky, Y.,Nyovanie, S.,Natarajan, A.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.,Findeis, M.,Hurwitz, A.,Van Dijk, M.,Buell, J.,Underwood, D.,Krogsgaard, M. (登録日: 2021-09-17, 公開日: 2022-11-02, 最終更新日: 2023-10-18)

• 主引用文献: Patskovsky, Y.,Natarajan, A.,Patskovska, L.,Nyovanie, S.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.B.,Findeis, M.A.,Hurwitz, A.,Van Dijk, M.,Chantzoura, E.,Yague, A.S.,Pollack Smith, D.,Buell, J.S.,Underwood, D.,Krogsgaard, M.; Molecular mechanism of phosphopeptide neoantigen immunogenicity.; Nat Commun, 14:3763-3763, 2023; PubMed: 37353482; DOI: 10.1038/s41467-023-39425-1

実験手法

X-RAY DIFFRACTION (1.92 Å)