7S7G

Crystal Structure Analysis of Human VLCAD

7S7G の概要

• エントリーDOI: 10.2210/pdb7s7g/pdb
• 分子名称: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: dehydrogenase, mitochondrial acyl-coa dehydrogenases, flavin adenine dinucleotide, deficiency, fatty acid oxidation, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 67611.99

構造登録者

Seo, H.-S.,Dhe-Paganon, S. (登録日: 2021-09-15, 公開日: 2022-09-28, 最終更新日: 2024-05-29)

• 主引用文献: Prew, M.S.,Camara, C.M.,Botzanowski, T.,Moroco, J.A.,Bloch, N.B.,Levy, H.R.,Seo, H.S.,Dhe-Paganon, S.,Bird, G.H.,Herce, H.D.,Gygi, M.A.,Escudero, S.,Wales, T.E.,Engen, J.R.,Walensky, L.D.; Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency.; Nat Commun, 13:3669-3669, 2022; PubMed: 35760926; DOI: 10.1038/s41467-022-31466-2

実験手法

X-RAY DIFFRACTION (1.34 Å)