7S6L

J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)

7S6L の概要

• エントリーDOI: 10.2210/pdb7s6l/pdb
• EMDBエントリー: 24879
• 分子名称: Spike glycoprotein, J08 fragment antigen binding heavy chain variable domain, J08 fragment antigen binding light chain variable domain, ... (5 entities in total)
• 機能のキーワード: covid, sars, cov-2, viral glycoprotein, spike, stabilizing mutations, coronavirus, ultrapotent antibody, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 455709.37

構造登録者

Ozorowski, G.,Torres, J.L.,Ward, A.B. (登録日: 2021-09-14, 公開日: 2022-05-11, 最終更新日: 2022-05-25)

• 主引用文献: Torres, J.L.,Ozorowski, G.,Andreano, E.,Liu, H.,Copps, J.,Piccini, G.,Donnici, L.,Conti, M.,Planchais, C.,Planas, D.,Manganaro, N.,Pantano, E.,Paciello, I.,Pileri, P.,Bruel, T.,Montomoli, E.,Mouquet, H.,Schwartz, O.,Sala, C.,De Francesco, R.,Wilson, I.A.,Rappuoli, R.,Ward, A.B.; Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.; Proc.Natl.Acad.Sci.USA, 119:e2120976119-e2120976119, 2022; PubMed: 35549549; DOI: 10.1073/pnas.2120976119

実験手法

ELECTRON MICROSCOPY (4 Å)