7S3Y

Structure ofrat neuronal nitric oxide synthase heme domain in complex with 7-((3-(2-(6-aminopyridin-2-yl)ethyl)phenoxy)methyl)quinolin-2-amine

7S3Y の概要

• エントリーDOI: 10.2210/pdb7s3y/pdb
• 分子名称: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (8 entities in total)
• 機能のキーワード: nitric oxide synthase inhibitor, heme enzyme, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100449.10

構造登録者

Li, H.,Poulos, T.L. (登録日: 2021-09-08, 公開日: 2022-09-14, 最終更新日: 2024-05-22)

• 主引用文献: Lewis, M.C.,Weerawarna, P.M.,Li, H.,Murarka, V.,Silverman, R.B.,Poulos, T.L.; Selective anti-MRSA inhibitors targeting bacterial nitric oxide synthase; To be published,

実験手法

X-RAY DIFFRACTION (2.08 Å)