7S3X

Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(((pyridin-2-ylmethyl)amino)methyl)phenoxy)methyl)quinolin-2-amine

Summary for 7S3X

• Entry DOI: 10.2210/pdb7s3x/pdb
• Descriptor: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor, heme enzyme, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 2
• Total formula weight: 100268.95

Authors

Li, H.,Poulos, T.L. (deposition date: 2021-09-08, release date: 2022-09-14, Last modification date: 2023-10-18)

• Primary citation: Lewis, M.C.,Weerawarna, P.M.,Li, H.,Murarka, V.,Silverman, R.B.,Poulos, T.L.; Selective anti-MRSA inhibitors targetting bacterial nitric oxide synthase; To be published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)