7S3X

Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(((pyridin-2-ylmethyl)amino)methyl)phenoxy)methyl)quinolin-2-amine

7S3X の概要

• エントリーDOI: 10.2210/pdb7s3x/pdb
• 分子名称: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
• 機能のキーワード: nitric oxide synthase inhibitor, heme enzyme, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100268.95

構造登録者

Li, H.,Poulos, T.L. (登録日: 2021-09-08, 公開日: 2022-09-14, 最終更新日: 2023-10-18)

• 主引用文献: Lewis, M.C.,Weerawarna, P.M.,Li, H.,Murarka, V.,Silverman, R.B.,Poulos, T.L.; Selective anti-MRSA inhibitors targetting bacterial nitric oxide synthase; To be published,

実験手法

X-RAY DIFFRACTION (1.95 Å)