7S2P

Crystal structure of the F337L mutation of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN

Summary for 7S2P

• Entry DOI: 10.2210/pdb7s2p/pdb
• Related: 7S2N
• Descriptor: Glucokinase 1, 2-{[(benzyloxy)carbonyl]amino}-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total)
• Functional Keywords: trypanosoma cruzi, chagas disease, transferase
• Biological source: Trypanosoma cruzi (strain CL Brener)
• Total number of polymer chains: 2
• Total formula weight: 85107.93

Authors

Carey, S.M.,Nettles, R.B.,Daneshian, L.,Chruszcz, M.,D'Antonio, E.L. (deposition date: 2021-09-03, release date: 2021-10-06, Last modification date: 2023-10-18)

• Primary citation: Carey, S.M.,Nettles, R.B.,Daneshian, L.,Chruszcz, M.,D'Antonio, E.L.; Crystal structure of the F337L mutation of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)