7RXJ
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
Summary for 7RXJ
Entry DOI | 10.2210/pdb7rxj/pdb |
Descriptor | Fab236 light chain, Fab236 heavy chain, Circumsporozoite protein, ... (4 entities in total) |
Functional Keywords | malaria, antibody, sporozoite, circumsporozoite protein, alpha-tsr domain, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 108511.11 |
Authors | Pholcharee, T.,Oyen, D.,Wilson, I.A. (deposition date: 2021-08-23, release date: 2022-03-16, Last modification date: 2024-04-03) |
Primary citation | Beutler, N.,Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,MacGill, R.S.,Garcia, E.,Calla, J.,Parren, M.,Yang, L.,Volkmuth, W.,Locke, E.,Regules, J.A.,Dutta, S.,Emerling, D.,Early, A.M.,Neafsey, D.E.,Winzeler, E.,King, C.R.,Zavala, F.,Burton, D.R.,Wilson, I.A.,Rogers, T.F. A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum. Plos Pathog., 18:e1010409-e1010409, 2022 Cited by PubMed: 35344575DOI: 10.1371/journal.ppat.1010409 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.345 Å) |
Structure validation
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