7RV5

Crystal structure of the BCL6 BTB domain in complex with OICR-9287

Summary for 7RV5

• Entry DOI: 10.2210/pdb7rv5/pdb
• Related: 7LWE 7LWF 7LWG
• Descriptor: Isoform 2 of B-cell lymphoma 6 protein, 2-[2-(4-benzylpiperidin-1-yl)-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-N-(3-chloropyridin-4-yl)acetamide (3 entities in total)
• Functional Keywords: immunity, inflammatory response, transcription repressor, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15036.78

Authors

Kuntz, D.A.,Prive, G.G. (deposition date: 2021-08-18, release date: 2022-08-24, Last modification date: 2023-10-18)

• Primary citation: Watson, I.,Isaac, M.; Structure of the BCL6 BTB domain; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.21 Å)